Achiral Peptoids and Variations for Treating Alzheimer's Disease

Description:

Technology # 15-18

 

A treatment to slow the progression of the disease. Alzheimer’s disease

 

Alzheimer’s disease is a devastating disease that progressively robs the memory and the mental abilities of the patient. There currently is no cure for Alzheimer’s, or even a treatment to slow the progression of the disease. Alzheimer’s disease affects more than 26.6 million people worldwide and is predicted to affect 1 in 85 people globally by 2050. Although there is no conclusive known cause of the disease, the presence of beta-amyloid plaques in the brain is associated with the disease and its symptoms. New peptoids have been created that prevent the aggregation of the beta amyloids, and may break up existing amyloids. These peptoids are currently being tested and research is on-going. The new peptoids may be developed into drugs which could be administered to Alzheimer’s patients to prevent further damage to their brains, and possibly even to reverse the effects of the disease

 

Application(s):

Alzheimer's disease, all diseases associated with amyloids, misfolding proteins, biomarker detections for amytoid beta and Alzheimer's disease, A beta modulation, A beta inhibition, A beta aggregation reversal, Type Il Diabetes treatment, Autism treatment, intranasal administration for neurodegenerative 

 

Advantage(s):

 

* Protease resistent

* Cost-effective production

* High bio availability

* Flexible molecule

* Low Immunogenicity

 

Technology:

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For additional information on the research, see this article

http://vpred.uark.edu/documents/techventures/tech_docs/acs_article_4-1-14.pdf

 

____________________________________________________ 

The invention is patent pending and is available for license. 

For interested parties seeking further information, feel free to contact:

 

Mark Allen Lanoue

Technology Manager / Tech Ventures

University of Arkansas

(479) 575-7243

malanoue@uark.edu

 

Patent Information:
App Type Country Serial No. Patent No. File Date Issued Date Expire Date
Provisional United States 62/184,057 6/24/2015    
For Information, Contact:
Mark Lanoue
Technology Manager
University of Arkansas
479-575-7243
malanoue@uark.edu
Inventors:
Shannon Servoss
James Turner
Melissa Moss
Keywords:
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