Engineered Fibroblast Growth Factor for Enhanced Wound Healing

Description:

Fibroblast Growth Factor (FGF) is a naturally occurring substance in the body that has many roles.  One of them is to help heal wounds, FGF causes the wound to grow new blood vessels and new nerves.  Currently FGF is used commercially to help in the healing of wounds, however, the version of FGF now used for this purpose is quickly degraded by the presence near a wound of thrombin – which is a blood coagulant.

A new type of engineered FGF has been invented that resists the degradation of thrombin, and has higher biological activity in the blood stream, thus leading to its being more effective in wound healing.  The new version of FGF has been shown to have twice the wound healing property of natural FGF. 

Advantages of the new FGF are;

1) Biologically extremely active

2) Thrombin Resistant

3) Thermo stable

4) Economically viable

5) Heparin independent mitogenic activity

 

 

Patent Information:
App Type Country Serial No. Patent No. File Date Issued Date Expire Date
Provisional United States 62/315,233 3/30/2016    
For Information, Contact:
Mark Swaney
Technology Licensing Officer
University of Arkansas
479-575-7243
mswaney@uark.edu
Inventors:
Suresh Kumar
Rebecca Kerr
Srinivas Jayanthi
David McNabb
David Zaharoff
Kartik Balachandran
Bhanuprasanth Koppolu
Keywords:
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