Search Results - Pharmaceutical

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A peptoid-peptide hybrid, NMEG-aCGRP, and its use in cardiovascular diseases
Technology #19-31The University of Arkansas has developed a novel Alpha CGRP, which is a potent vasodilator and has been shown to help in treating heart failure in rodent models. The problem with using it in human is its very short half-life in serum. It only last about 5-7 min. We have designed and created a new peptide that is more stable and resistant...
Published: 2/5/2020   |   Inventor(s): Shannon Servoss, Jay Potts, Ambrish Kumar, Donald Dipette
Keywords(s):  
Category(s): Medical, All, Pharmaceutical, Metabolic Diseases
Gold(I) and platinum(II) with isocyanide ligand complexes: Synthesis and biological activity
Technology # 19-20In our first project, new Pt(II) complexes were synthesized by the reaction of the precursor complexes cis,cis-[Me2Pt(μ-SMe2)2PtMe2], and cis-[(p-tolyl)2Pt(SMe2)2], with four and two equivalents of different types of isocyanide ligands (CNR; R = a; t-butyl, b; benzyl, and c; cyclohexyl isocyanide), respectively. All complexes were...
Published: 4/30/2019   |   Inventor(s): Mohammad Hassan Beyzavi
Keywords(s):  
Category(s): Medical, All, Pharmaceutical, Metabolic Diseases
Templated microgels with antimicrobial properties
Technology # 19-13A Novel approach to Templated microgels with antimicrobial properties The invented antimicrobial agents are microgels that are synthesized from commercially available monomers and a polymerizable pentadentate ligand. The ligand serves as a backbone for an immobilized dormant catalyst that can be conveniently activated by metal ion...
Published: 4/30/2019   |   Inventor(s): Babloo Sharma, Jessica Pickens, Susanne Striegler
Keywords(s):  
Category(s): Medical, All, Food Science & Nutrition, Pharmaceutical, Material Science
Peptoids and Methods for attenuating inflammatory response
Technology # 18-12PEPTOIDS AND METHODS FOR ATTENUATING INFLAMMATORY RESPONSEPeptoids are peptidomimetics that attain invulnerability to proteolytic degradation through repositioning of the side-chain from the α-carbon to the amide nitrogen. This invulnerability to pro-teases, as well as other qualities such as diminished immunogenicity, 10 enhanced...
Published: 4/30/2019   |   Inventor(s): Shannon Servoss, Melissa Moss, Lauren Wolf
Keywords(s):  
Category(s): Medical, All, Metabolic Diseases, Pharmaceutical
Peptoids and Methods for Treating Alzheimer's Disease
Technology # 12-14 (Also refer to 15-18)A Method of Treating Alzheimer's DiseaseAlzheimer’s disease is a devastating disease that progressively robs the memory and the mental abilities of the patient. There currently is no cure for Alzheimer’s, or even a treatment to slow the progression of the disease. Alzheimer’s disease affects...
Published: 4/30/2019   |   Inventor(s): Shannon Servoss, Melissa Moss
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical, All
Gold-Coated Carbon Nanotubes for Biomedical Applications
Technology #06-11The invention proposes a novel use of Gold coated Carbon Nanotubes (CNT) for bio-compatibility Carbon nanotubes (CNT's) are known to have particular optical qualities that make them interesting for possible biomedical applications. Specifically, the CNT's are very responsive to light in the near-infrared range (700 – 1110 nm wavelength)....
Published: 11/27/2018   |   Inventor(s): Jin-Woo Kim, Russell Deaton
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical, Materials & Nanotechnology, All
Self-assembled mechanical-energy-based amplifiers for probing interactions of DNA with small molecules and ions
Interactions between DNA and small molecules/ions are of great academic and pharmaceutical interest and importance. This is due to the interactions being essential for many fundamental processes in cells. For example, the formation of the secondary and higher-order structure of nucleotides, DNA repair, and genomic stability require the presence, meditation...
Published: 7/31/2018   |   Inventor(s): Yong Wang
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical, All
Achiral Peptoids and Variations for Treating Alzheimer's Disease
Technology # 15-18 A treatment to slow the progression of the disease. Alzheimer’s disease Alzheimer’s disease is a devastating disease that progressively robs the memory and the mental abilities of the patient. There currently is no cure for Alzheimer’s, or even a treatment to slow the progression of the disease. Alzheimer’s...
Published: 3/11/2016   |   Inventor(s): Shannon Servoss, James Turner, Melissa Moss
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical, All, Metabolic Diseases
Engineered Fibroblast Growth Factor for Enhanced Wound Healing
Technology # 16-06A technology for Enhanced Wound HealingFibroblast Growth Factor (FGF) is a naturally occurring substance in the body that has many roles. One of them is to help heal wounds, FGF causes the wound to grow new blood vessels and new nerves. Currently FGF is used commercially to help in the healing of wounds, however, the version of FGF...
Published: 12/22/2015   |   Inventor(s): Suresh Kumar, Rebecca Kerr, Srinivas Jayanthi, David Mcnabb, David Zaharoff, Kartik Balachandran, Bhanuprasanth Koppolu
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical, All
Improved Green Fluorescent Protein for Protein Manufacturing
Technology # 16-05Technology related to Green Fluorescent Protein Manufacturing When manufacturing proteins from bacteria that has DNA that has been engineered to produce a target protein, it is necessary to also engineer a tag onto the end of the target protein strand. The tag allows the target protein to be distinguished from the other non-target...
Published: 12/10/2015   |   Inventor(s): Robert Beitle, Suresh Thallapuranam, Joshua Sakon, David Mcnabb, Rudra Mukherjee
Keywords(s):  
Category(s): Medical, Biotechnology, Pharmaceutical, All, Food Science & Nutrition, Food Systems
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